In 2011,Hanahan and Weinberg added “Deregulating Cellular Energetics” and “Avoiding Immune Destruction” to the six p......

Mammalian target of rapamycin (mTOR) is a conserved Ser/Thr kinase that includes mTOR complex (mTORC) 1 and mTORC2.The m......

Furmonertinib was designed for the treatment of non-small cell lung cancer(NSCLC)patients with EGFR T790M mutation.In th......

Hepatocellular carcinoma(HCC)is one of the leading causes of cancer-related deaths,char-acterized by highly hypoxic tumo......

Breeding crops with enhanced nutrients is one of the major goals of plant breeding.Notably,plants intensively produce va......

Nitric oxide(NO)has emerged as an important signal molecule in plants,having myriad roles in plant devel-opment.In addit......

系统性红斑狼疮（SLE）是一种以产生大量自身抗体为特征并累及多器官多系统的自身免疫性疾病。巨噬细胞的极化不平衡及异常活化与SLE的......

The pace-of-life syndrome(POLS)hypothesis predicts that most variation in life history,physiology,and behavior among ind......

血管生成素样蛋白4（ANGPTL4）是主要在肝脏及脂肪组织表达的一种脂肪因子，属于血管生成素样蛋白家族。ANGPTL4通过影响血管生成、炎症......

Inflammatory bowel disease (IBD) is a chronic lifelong disease characterized by inflammation of the gastrointestinal tra......

Streptococcus mutans (S. mutans) is generally regarded as a major contributor to dental caries because of its ability to......

In this study,we investigated the in vivo behaviors of chiral cobalt oxide nanoparticles (Co3O4 NPs) stabilized with D-o......

欧洲临床营养与代谢协会（ESPEN）于2021年9月9―14日以在线方式召开第43届学术年会。大会对当前临床营养的热点话题展开广泛讨论。笔......

Long non-coding RNAs (lncRNAs) are poorly understood in insects.In this study,we performed genome-wide analysis of lncRN......

Gut dysbiosis is suggested to play a critical role in the pathogenesis of gout.The aim of our study was to identify the ......

Human intestinal bacteria play an important role in the metabolism of herbal medicines,leading to the variations in thei......

Astrapterocarpan (AP) is a bioactive constituent of Astragali Radix and was selected as a model compound for investigati......

Angelicae Pubescentis Radix (APR),a widely used traditional Chinese medicine (TCM),is mainly used to treat rheumatism an......

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Zinc-α2-glycoprotein (ZAG),encoded by the AZGP1 gene,is a major histocompatibility complex Ⅰ molecule and a lipid-mobi......

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The aim of this study was to analyze the influence of permeability glycoprotein (P-gp) expression on enrofloxacin (ENR) ......

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As a tool of durg delivery system,nanoparticles have been implemented in treating cancer and many other medical areas.Ho......

Rearing aquatic animals in an intensive manner involves the transformation of dietary inputs into fish biomass.This proc......

The continuing increase in aquaculture necessitates a responsible approach to supply and optimise the use of dietary nut......

Industrial ecology draws an analogy between industrial activity and natural ecosystems with the inherent implication tha......

N-Nitrosonornicotine(NNN)is considered to be one of the most carcinogenic compounds of the four conventionally measured ......

The arsenic containing drug roxarsone(3-nitro-4-hydroxy-phenylarsonicacid; ROX)is a frequently used animal feed additive......

Strawberry fruit is a rich source of phytochemicals and vitamins including anthocyanins,ascorbic acid(AsA)and folic acid......

Fruit development is a complex process involving dramatic changes in the transcriptional architecture.Sorbitol and sucro......

Lameness is a major issue influencing dairy cow health.Lameness in dairy cows not only causes loss of appetite, reductio......

Background: The Chinese population has been undergoing a rapid transition to a high-fat diet.Furthermore,monosodium L-gl......

Objective:Idiopathic scoliosis(IS)was considered as a multifactorial disease,with possible contributions from genetic fa......

Zn2+isanessentialcomponentofmetalloproteinases,andisrequiredfortheiractivityincartilage;however,theeffectofZn2+onnucleus......

Weexploredrelationshipsbetweenabdominalfatareaandblood glucose,bloodlipidlevel,andbonemineraldensity(BMD)inthemiddle-age......

Metabolomicanalysiswasperformedtodeterminethemetabolomicsignatureofosteonecrosisofthefemoralhead(ONFH),andtheunderlyingr......

Significant 2-[fluorine-18]fluoro-2-deoxy-D-glucose(18F-FDG)uptake by myocardium during the whole-body Positron Emission......

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Immunosuppression is an important intervention mechanism of tumor cells to the immune system,it can inhibit the normal f......

Objective Dysregulation of metabolism plays an important role in the development and progression of cancers,while the un......

Both kinetic metabolic fluxes and expression of metabolic genes display robust circadian rhythms across all major metabo......

Aim The preclinical studies of a novel angiotensin Ⅱ receptor 1 antagonist 2(4((1,7′dimethyl2′propyl1H ,3 ′H2,5 ′bi......

The melanocortin-4 receptor (MC4R) is an unusual G-protein coupled receptor that plays a critical role in energy homeost......

Objective: The aim of this study was to explore the metabolism of lipid molecules of follicular fluid from patients with......

Many aspects of energy metabolism, including glucose and lipid homeostasis and mitochondrial oxidative metabolism, are u......

Aim To investigate the intraindividual variation in activities of cytochrome P450 enzymes (CYP) in human liver microsome......

Aim Baicalein is the major flavonoid obtained from the Scutellaria root.Our previous studies have demonstrated that baic......