bleomycin相关论文
Background:We previously reported that interstitial injection of bleomycin (BLM) reduces the size of early-stage extracr......
Ni (Ⅱ) ions exacerbate bleomycin-induced pulmonary inflammation and fibrosis by activating Akt signa
目的 Ni is a kind of harmful heavy metals in particulate matter. We previously reported that Ni ions are strongly associ......
目的 In this study,we investigated the potential therapeutic effect of GA on pulmonary fibrosis in a ratmodel with bleom......
目的 This study used a bleomycin-induced acute lung injury in large rat models to observe the effects of normal human um......
A preliminary study about the treatment to low flow vascular malformations with foam and liquid mixt
Objective:To improve the low flow vascular malformations of hardening efficiency is the concern; study using foam and li......
Cell-surface Translocation of Annexin A2 contributes to bleomycin-induced pulmonary fibrosis by medi
Bleomycin,a widely used cancer drug,may give rise to a serious side effect,pulmonary fibrosis which is associated with s......
Idiopathic pulmonary fibrosis ([PF) is a chronic, progressive, and often fatal lung disease of unknown etiology, charact......
Purpose: Idiopathic pulmonary fibrosis(IPF)is a devastating and irreversible lung disease with few treatment options and......
Aim: Idiopathic pulmonary fibrosis (IPF), the most prevalent idiopathic interstitial pneumonia, has a median survival of......
Total glucosides of Danggui Buxue Tang ameliorates bleomycin-induced pulmonary fibrosis by inhibitin
Aim: Pulmonary fibrosis (PF) is a major cause of lung failure, but treatment remains ineffective.Our previous studies su......
Calcitriol inhibits bleomycin-evoked early pulmonary inflammatory response and epithelial-mesenchyma
Early pulmonary inflammation and epithelial-mesenchymal transition(EMT)play an important role in the pathogenesis of ble......
Astaxanthin inhibits lung fibrosis via down-regulation of TGF-β1-mediated Smads/ERK signaling pathwa
Objective: To investigate the effect of Astaxanthin (AX) on bleomycin (BLM)-induced lung fibrosis in rats and the underl......
Objective: To establish murine model of pulmonary fibrosis by Bleomycin and screen the anti-pulmonary fibrosis activity ......
Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomyc
Several reports indicate that melatonin alleviates bleomycin (BLM)-induced pulmonary fibrosis in rodent animals.Neverthe......
Cyclophosphamide abrogates the expansion of CD4+Foxp3+ regulatory T cells and enhances the effcacy o
Objective: Promotion of the proliferative expansion of CD4+Foxp3+ regulatory T cells (Tregs) is one of the side effects ......
Rapamycin attenuates bleomycin-induced pulmonary fibrosis in rats and the expression of metalloprote
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Intralesional Interstitial Injection of Bleomycin for Management of Extracranial Arteriovenous Malfo
Background Despite many advances in the treatment for extracranial arteriovenous malformations(AVMs),they still result......
瘢痕疙瘩是机体皮肤受到创伤后在修复过程中形成的一种病理性瘢痕，其形成机制尚不清楚，目前其治疗方法很多，国内外学者对此进行了大量......
目的研究布洛芬对博莱霉素诱导的小鼠肺纤维化的保护作用与TGF-β和MyD88的关系.方法通过气管内滴注博莱霉素复制小鼠肺纤维化模型......
Effects and possible anti-tumor immunity of electrochemotherapy with bleomycin on human colon cancer
AIM: To evaluate the anti-tumor effects and possible involvement of anti-tumor immunity of electrochemotherapy (ECT) emp......
CXC CHEMOKINE RECEPTOR 3 MODULATES BLEOMYCIN-INDUCED PULMONARY INJURY VIA INVOLVING INFLAMMATORY PRO
Objective To investigate the role of CXC chemokine receptor 3(CXCR3 ) in bleomycin-induced lung injury by using CXCR3 ge......
LOW DOSE PIRFENIDONE SUPPRESSES TRANSFORMING GROWTH FACTOR BETA-1 AND TISSUE INHIBITOR OF METALLOPRO
Objective To investigate the optimal dosage of pirfenidone for the treatment of pulmonary fibrosis induced by bleomycin ......
目的 评价中心静脉导管置入引流并胸腔内灌注金葡素注射液联合小剂量顺铂治疗恶性胸腔积液的疗效及不良反应.方法 64例恶性胸腔积......
ＥＸＰＲＥＳＳＩＯＮＯＦＴＧＦ－β１，ＰＤＧＦＡＮＤＩＧＦ－１ｍＲＮＡＩＮＬＵＮＧＯＦＢＬＥＯＭＹＣＩＮ－Ａ５－ＩＮＤＵＣＥＤＰＵＬＭＯＮＡＲＹＦＩＢＲＯＳＩＳＩＮＲＡＴＳＬｉＨａｉｃｈａｏ李海潮，ＨｅＢｉｎｇ何冰，ＱｕｅＣｈｅｎｇｌｉ阙呈立ａｎｄＷ...
EXPRESSIONOFTGF-β1, PDGFANDIGF-1mRNAINLUNGOFBLEOMYCIN-A5-INDUCEDPULMONARYFIBROSISINRATSLiHaichao......
目的:动态观察肺纤维化大鼠的内皮素合成和分布,了解内皮素(ENDOTHELIN,ET)与特发性肺纤维化发生发展的关系.方法:采用放射免疫法......
目的 研究本实验室表达的重组人干扰素-β-1a (IFN-β-1a)对BALB/C小鼠硬化症的疗效.方法 通过皮下注射博来霉素制BALB/C小鼠硬化......
目的 ABVD化疗方案中博来霉素治疗指数较低,本文报道1例死亡病例供临床参考,旨在提示临床谨慎应用.方法 报道1名74岁的中国男性患......
目的 观察石荠芋总黄酮(MSF)对博来霉素致大鼠肺纤维化的干预作用,并初步探讨其机制.方法 60只SD大鼠随机分为正常组,模型组,阳性......
目的研究昆布提取物(Okam)对博莱霉素(Bleomycin)所致大鼠肺间质纤维化的抑制作用。方法Wistar大鼠经气管内注入博莱霉素诱导肺纤......
目的探讨PI3K/Akt/HIF-1α信号通路在博来霉素(BLM)诱导的小鼠肺纤维化中的作用机制。方法 56只C57BL/6小鼠随机分为对照组和实验......
目的 探讨RAD52、XRCC2、XRCC4基因多态性与1,3-丁二烯(BD)作业工人DNA修复能力的关系.方法 利用染色体断裂试验评价60名BD职业暴......
,Dose evaluation of therapeutic radiolabeled bleomycin complexes based on biodistribution data in wi
Bleomycins (BLMs), as tumor-seeking antibiotics, have been used for over 20 years in treatment of several types of cance......
目的 观察骨化三醇[1,25(OH)2D3]对博来霉素诱导的小鼠肺纤维化的干预作用,并初步探讨其作用机制.方法 将90只6～8周龄的SPF级雄性C5......
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目的建立博来霉素诱导小鼠肺纤维化模型，观察ROCK抑制剂法舒地尔对肺纤维化的干预作用；同时体外培养NIH3T3成纤维细胞，观察法舒地尔对......
Aim: To study the protective effects of a triptolide-derived, novel compound,(5R)-5-hydroxytriptolide (LLDT-8), on bleom......
,Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induce
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,siRNA against plasminogen activator inhibitor-1 ameliorates bleomycin-induced lung fibrosis in rats
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,Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosis thro
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,Protective effects of a bacterially expressed NIF-KGF fusion protein against bleomycin-induced acut
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Jinbei Oral Liquid ameliorates bleomycin-induced idiopathic pulmonary fibrosis in rats via reversion
Objective: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal interstitial lung disease with high mortality......
Pyunkang-hwan (Pyunkang-Tang) ameliorates air pollutant-induced inflammatory hypersecretion of airwa
OBJECTIVE: To investigate the effect of Pyunkanghwan(Pyunkang-tang) extract(PGT) on secretion of airway mucin in an expe......
目的观察粒细胞集落刺激因子(G-CSF)动员自体骨髓源性细胞(BMDC)对博来霉素所致小鼠肺损伤的修复作用方法采用随机数字表法将60只......
近年来,宫颈癌的发病率呈明显上升趋势,且发病年龄呈年轻化趋势.传统放疗对巨块型(直径≥4cm)及局部晚期宫颈癌的局部控制率较低,......
Rapamycin attenuates bleomycin-induced pulmonary fibrosis in rats and the expression of metalloprote
Background Idiopathic pulmonary fibrosis (IPF) is the most common and devastating form of interstitial lung disease (ILD......
目的观察平阳霉素治疗小儿皮肤海绵状血管瘤的疗效。方法选择2006年5月—2013年4月收治的小儿皮肤海绵状血管瘤患者277例,采用平阳......
