Nephrotoxicity相关论文
Altered cisplatin pharmacokinetics during nonalcoholic steatohepatitis contributes to reduced nephro
Disease-mediated alterations to drug disposition constitute a significant source of adverse drug reactions.Cisplatin(CDD......
Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malig......
Arsenic from environmental contamination is a risk factor for kidney disease,and the clinical use of arsenic also trigge......
This study was conducted to investigate the value of lycopene in overcoming renal damage induced by colistin sufate.Lyco......
The expanding development and production of nanomaterials have diverse and reach potential benefits in many fields,such ......
Evaluation of Two Biomarkers as Early Indicators for Assessment of Gentamycin-induced Nephrotoxicity
The aminolycoside Gentamicin is a widely used antibiotic, applied in equine medicine.Despite its clinical use, concerns ......
Gentamicin is a member of Aminoglycosides which has represented highly effective antimicrobial agents especially in Gram......
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Endoplasmic reticulum stress involved in renal autophagy and dysfunction triggered by CdTe-quantum d
Quantum dots(QDs)have been widely employed in biomedical applications including biosensors,biomedical imaging,and drug d......
Pre-treatment serum C-reactive protein level is an independent risk factor for development of nephro
High-dose vancomycin treatment increases the likelihood of vancomycin-related nephrotoxicity.C-reactive protein(CRP)is a......
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Identification of novel indicators of Andrographolide sodium bisulfate nephrotoxicity in a Rats mode
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越来越多的证据表明,过多脂质在非脂肪组织沉积将通过“脂毒性”对器官造成损害.肾脏脂质过多沉积可能通过氧化应激、内质网应激、......
Tisplatin is one of the valuable icancer agents against several types of neoplasm. However, nephrotoxicity is the major ......
In vitro study of the nephrotoxicity of total Dahuang (Radix Et Rhizoma Rhei Palmati) anthraquinones
OBJECTIVE:To examine changes in the morphology and physiological functions of human proximal tubular epithelial cells (H......
Objective: To evaluate the nephroprotective effect of defatted mehtanolic extract and aqueous extract of Murraya koenigi......
Synergistic renoprotective effect of a compiled branched-chain amino acids and Cymbopogon schoenanth
Objective: To better investigate the protective role of branched-chain amino acids (BCAAs) and Cymbopogon schoenanthus (......
p-Coumaric acid ameliorates ethanol-induced kidney injury by inhibiting inflammatory cytokine produc
Objective: To examine the effects of p-coumaric acid on ethanol-induced kidney injury in Swiss Wistar rats. Methods: Eth......
Probiotic bacteria attenuates cisplatin-induced nephrotoxicity through modulation of oxidative stres
Objective: To investigate the effects of probiotic bacteria on cisplatin (CP)-induced nephrotoxicity. Methods: In the pr......
Microproteinuria for detecting calcineurin inhibitor-related nephrotoxicity after liver transplantat
AIM: To investigate whether microproteinuria could be used as an early and sensitive indicator to detect calcineurin inh......
Danshen,an efficacious agent for cardiovascular diseases,has been found to play an essential role in kidney injury.In th......
目的 观察转化生长因子(TGF)-β1在他克莫司大鼠肾毒性中的作用.方法 将SD大鼠24只随机分成对照组、CsA组、FK506组和FK506+Dil组,......
目的 比较不同渗透浓度X线造影剂对高胆固醇血症大鼠的肾毒性,探讨己酮可可碱(PTX)对造影剂肾毒性是否有保护作用.方法 48只健康雄......
Experimental Study on Effect of Cordyceps Sinensis in Ameliorating Aminoglycoside Induced Nephrotoxi
Ｅｘｐｅｒｉｍｅｎｔａｌ Ｓｔｕｄｙ ｏｎ Ｅｆｆｅｃｔ ｏｆ Ｃｏｒｄｙｃｅｐｓ Ｓｉｎｅｎｓｉｓ ｉｎ Ａｍｅｌｉｏｒａｔｉｎｇ Ａｍｉｎｏｇｌｙｃｏｓｉｄｅ Ｉｎｄｕｃｅｄ ＮｅｐｈｒｏｔｏｘｉｃｉｔｙＬＩＬｅｉ－ｓｈｉ；ＺＨＥＮＧＦｅｎｇ；Ｌ...
Experimental Study on Effect of Cordyceps Sinensis in Ameliorating Aminoglycoside Induced Nep......
本研究旨在通过大样本前瞻性队列研究,评价万古霉素稳态谷浓度与临床疗效和安全性之间的相关性,从而验证指南将万古霉素稳态谷浓度......
目的:研究万古霉素血药谷浓度与死亡率、治疗失败率和肾毒性之间的关系.方法:系统检索PubMed、Embase、Cochrane图书馆和三个中文......
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,Emodin ameliorates cisplatin-induced apoptosis of rat renal tubular cells in vitro by activating au
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,Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototo
Etimicin (ETM),a fourth-generation aminoglycosides (AGs),is now widely clinically used in China due to its high efficacy......
In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption e
Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development.Herein,an in s......
富马酸替诺福韦二吡呋酯（ TDF ）用于治疗慢性乙型肝炎（ CHB ）和人类免疫缺陷病毒（HIV）感染。 TDF对HIV及乙型肝炎病毒（HBV）均具有良好的抗......
Nephroprotective activity ofSolanum xanthocarpum fruit extract against gentamicin-induced nephrotoxi
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的 探讨血、尿β_2-微球蛋白(β_2-mG)检测对顺铂化疗时肾毒性早期诊断的临床意义.方法 动态监测64例共接受HD-DDP(80～110 mg/m~2......
Carissa carandas Linn. fruit extract ameliorates gentamicin-induced nephrotoxicity in rats via atten
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induce
Paracetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating th......
马兜铃酸(Aristolochic acids,AAs),主要是由来源于马兜铃科属植物的8-methoxy-6-nitro-phenanthro-(3,4-d)-1,3-dioxolo-5-carbox......
Objective We tested whether melamine nephrotoxicity was exacerbated by urate(a typical component of renal stones in huma......
Objective: To observe the clinical effect of Yiqi Jianpi Bushen recipe (YQJPBS, 益气健脾补肾方) in antagonizing nephroto......
在建立了大鼠喉移植动物模型的基础上,本研究对环孢素 A(CsA)的肝肾毒性作用进行了形态学观察。突验共分3组,接受 CsA 治疗的两个......
本文观察了中药钙拮抗剂汉防己甲素对大鼠环孢素A肾毒性(CsA-NT)的防护作用.雄性Wistar大鼠用CsA 50mg·kg-1/d灌胃7天导致急性CsA......
目的：评价胱抑素C（Cys C）用于监测化疗药物导致恶性肿瘤患者肾功能损害的可行性和可靠性。方法检测30例晚期恶性肿瘤患者化疗前后血清......
顺铂为临床上广泛应用治疗多种实体肿瘤的化疗药物,但在正常组织器官中的不良反应,尤其是肾毒性限制了其临床应用.应用顺铂治疗后,......
肾脏是人体最大的排泄器官,接受约25％心搏出血流总量.人体大多数药物的代谢和排泄任务都由肾脏承担,使得肾脏成为药物毒副作用最常......
目的：探讨大鼠急性肾损伤后尿液新生物标志物时间和剂量依懒性，以寻找敏感和特异的新生物标志物。方法SD 大鼠分别 i m给予硫酸庆大......
目的基于网络药理学分析斑蝥素致肾毒性分子机制。方法首先检索TCMSP、CTD、Pubchem、Uniprot数据库整合斑蝥素潜在作用靶点,同时......
目的探讨预先投予GSH和牛磺酸对汞急性肾毒性的影响.方法将32只Wistar大鼠随机分为对照、HgCl2染毒、GSH+HgCl2和牛磺酸+HgCl2 4组......
对吕梁地区１０个县（市）的食品卫生监督文书的使用制作质量进行了检查分析，结果表明，卫生监督文书使用不全，制作上存在缺项、错项、错别字、......
目的：观察肾移植受者ABCB1 3435C〉T基因多态性对环孢素（CsA）所致慢性肾毒性的影响.方法：1995～2010年行肾移植术患者344例,根据临床指征......
目的研究银杏黄酮（GBE）对卡铂（CBDCA）所致大鼠肾氧化损伤的保护作用，并探讨其可能机制。方法灌胃给予大鼠GBE后腹腔内注射CBDCA，5d后检测......
加强劳动卫生法制管理，实行《劳动卫生许可证》制度，是保护广大劳动者健康的有力举措。本又沦述了进一步加强劳动卫生法制管理的法律......
