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目的:研究头孢菌素类药物与其他药物联合使用时产生不良反应的情况。方法:选取2014年1月~2015年12月期间在我院使用头孢菌素类药物治疗的80患者作为研究样本,根据使用的头孢菌素类药物的不同,将患者进行分组,分别为对照组(n=40)和观察组(n=40),对照组患者使用单纯的头孢菌素类药物,观察组的使用头孢菌素类药物联合其他药物,观察两组患者的药物不良反应并分析,并且根据患者的用药效果和不良反应制定相应的应急对策。结果:观察组患者的药物不良反应发生率高于对照组,两组存在显著性差异,有统计学意义(P<0.05)。结论:在使用头孢菌素类药物治疗各类疾病的过程中,必须依据患者的病情选择有效合理的治疗方案,同时应对药物给患者带来的药物不良反应采取适当的措施,降低患者的药物不良反应,提高对患者的治疗效果。
Objective: To study the adverse reactions of cephalosporins when combined with other drugs. Methods: Eighty-eight patients treated with cephalosporins in our hospital from January 2014 to December 2015 were selected as the study samples. According to the different cephalosporins used, the patients were divided into control group (n = 40) and observation group (n = 40). The patients in the control group were treated with simple cephalosporins. The patients in the observation group were treated with cephalosporins in combination with other drugs. The adverse reactions of the two groups were observed and analyzed. And according to the patient’s medication effects and adverse reactions to develop appropriate emergency response. Results: The incidence of adverse drug reactions in the observation group was higher than that in the control group. There was a significant difference between the two groups (P <0.05). Conclusion: In the process of using cephalosporins to treat various diseases, effective and reasonable treatment plan must be selected according to the patient’s condition, and appropriate measures should be taken to cope with the adverse drug reactions caused by the drugs to the patients so as to reduce the patient’s drug problems Response, improve the treatment of patients.