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血管钙化在终末期肾病患者很常见,其过程与骨形成相似,是有组织的主动调节过程,涉及许多促进和抑制钙化因素。其中骨形成蛋白在血管钙化中扮演着重要的角色。骨形成蛋白2和骨形成蛋白7与血管钙化的可能相关作用是目前研究最多的。
Vascular calcification is very common in patients with end-stage renal disease, and its process is similar to bone formation and is an organized and active regulatory process involving many factors that promote and inhibit calcification. Among them, bone morphogenetic protein plays an important role in vascular calcification. The possible correlation between BMP2 and BMP7 and vascular calcification is currently the most studied.