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人类乳癌中雌、孕激素受体的存在,与肿瘤对激素治疗的有利反应和生存率的增加有关联,其他研究也报导子宫内膜腺瘤中孕激素受体和对治疗反应的关系。在现今的妇科肿瘤中,有效治疗卵巢癌是个突出问题,特别是激素治疗显示有价值时任何有关卵巢瘤的预示性资料都会受到认真的评价。虽然卵巢间质本身是甾体激素的主要来源,但一般上皮性卵巢癌是由被覆卵巢的间皮改变而来,它和苗勒氏管衍生的生殖道肿瘤一样对性激素有反应。最近的许多研究指出:雌、孕、雄激素受体以不同的浓度和结合形式存在于卵巢癌中,该报告指出:激素治疗开始前、在正常良性和恶性卵巢中雌、孕激素受体的情况。本文旨在表明可以把测定性甾体激素受体状况作为预测卵巢癌患者的长期存活和对激素治疗反应的资料。肿瘤标本系来自71例患卵巢良、恶性肿瘤的手术标本。正常卵巢组织则系来自32例绝经期前后行
The presence of estrogen and progesterone receptors in human breast cancer is associated with favorable tumor response to hormone therapy and increased survival, and other studies report the association of progesterone receptors with response to treatment in endometrial adenomas. In today’s gynecological tumors, the effective treatment of ovarian cancer is a prominent issue, in particular, hormone therapy has shown any value when any predictive information on ovarian cancer will be seriously evaluated. Although the ovarian stroma itself is the main source of steroid hormones, epithelial ovarian cancer is generally epithelial ovarian mesothelioma changed from Murex’s tube derived reproductive tract tumors on the same sex hormone response. Many recent studies have indicated that estrogen, progesterone and androgen receptors are present in ovarian cancer at different concentrations and binding forms, and the report states that the estrogen and progesterone receptor Happening. This article aims to demonstrate that determinant steroid hormone receptor status can be used as a predictor of long-term survival and response to hormone therapy in patients with ovarian cancer. Tumor specimens from 71 cases of ovarian benign and malignant tumors of the surgical specimens. Normal ovarian tissue is derived from 32 cases before and after menopause