论文部分内容阅读
本文报道了BALB/c和C 57 BL/6两系中未用于试验的3000只青年、800只退役的两性种用小鼠中赘生物性和非赘生物性病损的发病情况。在BALB/c系小鼠中,最常见的非赘生物性病损有:肝脏脂肪变态、子宫含铁血黄素沉着和无机化、睾丸萎缩、卵巢囊肿、以及肾上腺包膜下纺锤细胞增生;最常见的赘生物则有:肺肿瘤、肝细胞赘生物、副泪腺腺癌(Harderian adenomas)和子宫息肉。在C 57 BL/6系小鼠中,常见的非赘生物性病损有:肺淋巴组织积
This article reports the incidence of neoplastic and non-neoplastic lesions in 3,000 young and 800 retired male and female mice of both BALB / c and C 57 BL / 6 families that were not used for testing. In BALB / c mice, the most common non-neoplastic lesions are: fatty liver metamorphosis, uterine hemosiderrosis and inorganisation, testicular atrophy, ovarian cysts, and adrenal enveloped spindle cell proliferation; the most common Of the neoplasms are: lung tumors, liver cell neoplasms, sub-lacrimal adenocarcinoma (Harderian adenomas) and uterine polyps. Common non-neoplastic lesions in C57BL / 6 mice are: lung-lymphoid tissue mass