转移因子 (TF)具有增强甲肝疫苗热稳定性的作用 ,其效果与 1M的MgCl2 相当 ,加入TF的甲肝疫苗在 4～ 8℃保存 6个月、室温保存 2 1天、37℃保存 7天 ,滴度基本不变 ,仍在6 5LgCCID50 /ml的合格范围内。当提高保存温度时 ,这种作用效果更明显 ;另外 ,TF还具有一定的免疫佐剂作用 ,甲肝疫苗与TF混合后免疫小白鼠 ,阳转率 (10 / 10 )比对照组 (8/ 10 )高 ,几何平均滴度是对照组的 1 6 3倍 Transfer factor (TF) has the effect of enhancing the thermal stability of hepatitis A vaccine, and its effect is equivalent to that of 1M MgCl2. The hepatitis A vaccine added with TF is preserved at 4 ~ 8 ℃ for 6 months, stored for 21 days at room temperature and stored at 37 ℃ for 7 days, Titers remained essentially unchanged and remained within the eligible range of 6 5Lg CCID50 / ml. In addition, TF also had certain immune adjuvant effect. After being mixed with TF, the mice were immunized with the immunization of mice. The positive rate (10/10) was higher than that of the control group (8/10 ) High, the geometric mean titer is 136 times that of the control group