目前中西药联用已相当普遍,中西药联合制剂不断问世,受到了愈来愈广泛重视。中西药联用,其目的是为了提高疗效和减少副作用,但如应用配伍不合理,也可产生相反的效果,本文就搜集到的几种中西药联用配伍不合理现象,从药理、药化方面进行了分析与探讨,并归纳为六种类型:　　1、形成难溶物质,影响疗效。2、产生毒性导致药源性疾病。3、相互拮抗,影响疗效。4、酸碱中和改变药物成份。5、抑制微生物或破坏酶的作用。6、增加中毒性,造成不良后果。 At present, the combination of traditional Chinese and western medicine has become quite common, and the joint preparations of Chinese and western medicine have come out continuously and are receiving more and more attention. Chinese and Western medicine combined, its purpose is to improve the efficacy and reduce side effects, but if unreasonable application compatibility can also have the opposite effect, this collection of several Chinese and Western medicine combined unreasonable phenomenon, from the pharmacology, Analyzed and discussed, and summarized into six types: 1, the formation of insoluble substances, affect the efficacy. 2, resulting in drug-induced toxicity of the disease. 3, mutual antagonism, affect the efficacy. 4, acid and alkali to change the drug ingredients. 5, inhibit the role of microorganisms or destroy enzymes. 6, increase the toxicity, resulting in adverse consequences.