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目的:分析在肺动脉高压右心功能不全的治疗中应用阿魏酸钠的临床效果。方法:选择2013年3月—2015年3月间我院接收治疗的肺动脉高压右心功能不全患者198例为观察对象,随机将198例患者分为阿魏酸钠组及常规治疗组,各99例,阿魏酸钠组在常规治疗组基础上给予阿魏酸钠治疗,对两组治疗效果进行观察。结果:阿魏酸钠组PaO2、SaO2改善程度比常规治疗组明显,阿魏酸钠组RVD与PASP改善程度比常规治疗组明显,阿魏酸钠组治疗总有效率为98.0%,明显比常规治疗组的83.8%高,差异具有统计学意义(P<0.05),两组在治疗过程均未出现严重不良反应。结论:阿魏酸钠应用到肺动脉高压右心功能不全的治疗可实现良好临床效果,使患者右心功能得到有效改善,且用药安全性较为理想,不会出现严重不良反应,具有进一步推广应用的临床价值。
Objective: To analyze the clinical effect of sodium ferulate in the treatment of pulmonary hypertension with right ventricular dysfunction. Methods: A total of 198 patients with right ventricular dysfunction admitted to our hospital from March 2013 to March 2015 were selected as subjects. 198 patients were randomly divided into sodium ferulate group and conventional treatment group Cases, sodium ferulate group in the conventional treatment group given sodium ferulate treatment, the two groups observed the effect of treatment. Results: The improvement of PaO2 and SaO2 in sodium ferulate group was more obvious than that in conventional treatment group. The improvement of RVD and PASP in sodium ferulate group was more obvious than that of conventional treatment group. The total effective rate of sodium ferulate group was 98.0% The treatment group was 83.8%, the difference was statistically significant (P <0.05), both groups did not appear in the treatment of serious adverse reactions. Conclusion: The application of sodium ferulate to the treatment of right ventricular dysfunction in pulmonary hypertension can achieve good clinical results, effectively improve the right heart function, and the medication safety is ideal, no serious adverse reactions, with further promotion and application Clinical Value.