由于下丘脑-垂体后叶病变导致抗利尿激素(ADH)缺乏而引起的多尿、烦渴,多饮、低比重尿和低渗尿综合征,称中枢性尿崩症(又称下丘脑-垂体性尿崩症)。与肾脏对ADH反应缺陷引起的肾性尿崩症不同,前者对ADH替代治疗有效,而后者无效。中枢性尿崩症按病因可分为原发性(原因不明,可能为合成ADH酶缺陷)、继发性(颅脑创伤、肿瘤、炎症、浸润性疾病及血管病变)与家族遗传性(仅占％)尿崩症;按起病方式分为暂时性、永久性与三相 As the hypothalamus - pituitary disease leading to the lack of antidiuretic hormone (ADH) caused by polyuria, polydipsia, polydipsia, low specific gravity and hypotonic urinary syndrome, said central diabetes insipidus (also known as hypothalamic - Pituitary diabetes insipidus). In contrast to nephrogenic diabetes insipidus, which is caused by defects in kidney response to ADH, the former is effective for ADH replacement therapy and the latter is ineffective. Central diabetes insipidus due to etiology can be divided into primary (unexplained, may be the synthesis of ADH enzyme defects), secondary (traumatic brain injury, cancer, inflammation, invasive disease and vascular disease) and familial hereditary Accounting for%) diabetes insipidus; according to onset is divided into temporary, permanent and three-phase