二尖瓣脱垂(下称:二脱)在临床上较为常见,正常人群中国外报告为6％～21％不等,且女性患者是男性的3倍,部分患者有家族性发病倾向。1981年国外首次报告Graves病(下称:甲亢)患者合并二脱发生率约43％,明显高于正常人群。1985年又有类似报告,国内也有个例报告。我们随机观察30例甲亢患者,其中合并二脱者10例占33(％),而相应对照组中仅2例(占6.7％)。 Mitral valve prolapse (hereinafter referred to as: two off) is more common in clinical practice, the Chinese population reported 6% to 21% of normal population, and women are three times the number of men, some patients have a familial tendency. In 1981, the first report of Graves disease (hereinafter referred to as: hyperthyroidism) in patients with secondary stripping occurred in about 43%, significantly higher than the normal population. There was a similar report in 1985 and there was also a case report in China. We randomly observed 30 patients with hyperthyroidism, of which 10 (33%) were complicated with two offs, compared to only 2 (6.7%) in the corresponding control group.