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目的了解随州市2010年手足口病流行病学和病原学特征,为手足口病防控提供科学依据。方法统计分析随州市2010年的手足口病例发病报告数据,对所有重症病例、所辖县市每月随机抽取的5例轻症病例采样进行病原学检测分析。结果 2010年随州市共报5 284例手足病病例,全年均有发病,3～5月发病较多,主要为4岁以下儿童,5～7月报告11例重症病例;125例病例病原学检测,EV 71阳性19例,阳性率为15.2%;Cox A 16阳性25例,阳性率为20.0%,PE阳性15例,阳性率为12%,1～4月检出的手足口病原体为Cox A 16,8～12月检出的病原体为EV 71,5～7月Cox A 16和EV 71均有检出。结论随州市2010年手足口病发病主要在春夏季,4岁以下儿童,病原体上半年以Cox A 16为主,下半年以EV 71为主,引起死亡和重症的病原体为EV 71,提示重点人群是4岁以下EV 71感染病例。
Objective To understand the epidemiological and etiological characteristics of hand, foot and mouth disease in Suizhou City in 2010, and to provide a scientific basis for prevention and control of hand, foot and mouth disease. Methods The data of incidence of hand, foot and mouth disease in Suizhou City in 2010 were statistically analyzed. The etiology and pathogenicity of 5 cases of mild cases sampled every month in all severe cases and counties and cities were analyzed. Results In 2010, a total of 5 284 cases of hand-foot-and-mouth disease were reported in Suizhou City. There were all cases of disease in Suizhou City in 2010, with more incidence in March-May, mainly children under 4 years old, 11 severe cases in May-July and 125 cases of pathogenic The positive rate of Cox A 16 was 25, the positive rate was 20.0%, and the positive rate of PE was 15% (positive rate was 12%). The pathogen of hand, foot and mouth was detected from January to April as Cox The pathogen detected by A 16 and 8-12 was EV 71, and Cox A 16 and EV 71 were detected in May-July. Conclusion The incidence of hand-foot-mouth disease in Suizhou in 2010 was mainly in spring and summer, children under 4 years old. The pathogen was mainly Cox A 16 in the first half of the year. EV 71 was the second half of the year. The pathogen causing death and severe illness was EV 71, EV 71 infections under 4 years of age.