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目的了解莱州市腹泻患者致泻性弧菌的构成及在不同时间、人群中的分布和耐药性状况,为综合防治工作提供依据。方法采集2011~2012年莱州市腹泻患者标本,检测致泻性弧菌。结果 2011~2012年合计检测157份腹泻患者标本,检出致泻性弧菌42株,检出率为26.75%,其中副溶血性弧菌12株(占28.57%)、气单胞菌24株(占57.14%)、河弧菌、拟态弧菌、类志贺邻单胞均为2株(占4.76%),未检出霍乱弧菌和创伤弧菌。致泻性弧菌检出率,男性为25.53%、女性为28.57%(P>0.05);21~30岁为35.00%,31~40岁为32.00%(P>0.05),8、6月检出率高达42.86%(15/35)和36.36%(4/11),不同月份差异有统计学意义(P<0.05)。致泻性弧菌对氨苄西林的耐药率高达91.67%,但对其他大多数抗生素敏感。结论莱州市腹泻患者由气单胞菌和副溶血性弧菌引起的比例较高,且主要发生在夏秋季节,可用β-内酰胺类、氨基糖苷类、喹诺酮类等抗生素作为临床治疗用药。
Objective To understand the composition of Vibrio diarrhealus in diarrhea patients in Laizhou and their distribution and drug resistance in different time and population, so as to provide the basis for comprehensive prevention and control. Methods Samples of diarrhea patients from 2011 to 2012 in Laizhou were collected to detect Vibrio cholerae. Results A total of 157 samples of diarrhea were detected in 2011 and 2012, respectively, and 42 strains of Vibrio cholerae were detected, the detection rate was 26.75%. Twelve strains (28.57%) of V. parahaemolyticus and 24 strains of Aeromonas (57.14%), Vibrio cholerae, Vibrio mimicus, and Shiga neighbors were all 2 (4.76%). Vibrio cholerae and Vibrio vulnificus were not detected. The detection rate of Vibrio alginolyticus was 25.53% in males and 28.57% in females (P> 0.05), 35.00% in 21-30 years and 32.00% in 31-40 years (P> 0.05) The rates were as high as 42.86% (15/35) and 36.36% (4/11), respectively, with significant differences between months (P <0.05). Vibrio ampulococcus Vibrio ampicillin resistance rate as high as 91.67%, but most other antibiotics sensitive. Conclusion Laizhou diarrhea patients caused by Aeromonas and Vibrio parahaemolyticus caused by a higher proportion, and mainly occurs in summer and autumn, the available β-lactams, aminoglycosides, quinolones and other antibiotics as a clinical treatment.