弓形体病为弓形虫感染引起的传染病,弓形虫几乎能感染所有温血动物。感染弓形虫对健康人群的影响不大,但是对未出生的胎儿或免疫系统较差的人群则会产生较大的危害,甚至致死。一直以来,弓形体病治疗的研究焦点都集中在如何对弓形虫自身产生作用,而乔治亚大学的研究人员认为可以将虫体和宿主两者皆作为治疗靶点。研究人员发现,联用阿托伐他汀与唑来膦酸可治愈弓形体病,相关的研究结果发表在近期出版的《PLoS Pathogens》上。乔治亚大学的研究人员在初期试验中发现,多种不同降胆固醇药物阿托伐他汀和骨质疏松治疗药唑来膦酸的复方制剂,如立普妥、择泰等,皆能影响哺乳动物宿主及寄生虫,最终可阻断寄生虫的复制及疾病的传播。这2 Toxoplasmosis is an infection caused by Toxoplasma gondii, which can infect almost all warm-blooded animals. Toxoplasma gondii infection has little effect on healthy people, but it can cause great harm to even unborn babies or people with poor immune system. Toxoplasmosis has long been the focus of research on how Toxoplasma gondii itself has a role, and researchers at the University of Georgia believe it is possible to target both the parasite and the host. The researchers found that the combination of atorvastatin and zoledronic acid can cure toxoplasmosis, the findings of which are published in the recently published “PLoS Pathogens.” Researchers at the University of Georgia found in initial trials that various combinations of cholesterol-lowering atorvastatin and osteoporosis-treated zoledronic acid, such as Lipitor and choice Thai, can affect mammalian hosts And parasites, eventually blocking the replication of parasites and the spread of disease. This 2