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为探索小儿原发性肾小球疾病中医辨证的客观指标,对78例原发性肾小球疾病的患儿进行中医辨证分型与临床、病理关系的分析研究。中医辨证分5型;气虚、阳虚、阴虚、气阴两虚和湿热型。西医临床分型:肾病综合征(肾病)和肾炎型。病理类型系根据1979年和1982年WHO公布的肾小球疾病的分类方案。结果肾病型51例和肾炎型27例中,分别有气虚型36例、10例,阳虚型3例、2例,阴虚型2例、0例,气阴两虚型8例、5例,湿热型2例、10例。辨证分型与病理类型的关系:气虚为系膜增生性肾炎(MsPGN)和MsPGN+局灶节段性肾小球硬化(FSGS),阳虚为硬化性肾炎(SGN)、FSGS、MsPGN+FSGS和MsPGN,阴虚为MsPGN,气阴两虚为MsPGN、MsPGN+FSGS和毛细血管内增生性肾炎(EPGN),湿热为局灶性肾炎(FGN)、EPGN和MsPGN。表明肾组织病理检查可为中医辨证提供客观指标,并可指导临床辨证施治。
In order to explore the objective index of syndrome differentiation of traditional Chinese medicine in children with primary glomerular disease, 78 cases of primary glomerular disease were diagnosed by TCM syndrome differentiation and clinical and pathological analysis. TCM syndrome type 5; qi, yang, yin deficiency, Qi and Yin Deficiency and damp-heat type. Western clinical classification: nephrotic syndrome (nephropathy) and nephritis type. The pathological type is based on the classification scheme of glomerular diseases published by WHO in 1979 and 1982. Results Among the 51 cases of nephropathy and 27 cases of nephritis, there were 36 cases of qi deficiency type, 10 cases of yang deficiency type, 3 cases of yang deficiency type, 2 cases of yin deficiency type, 2 cases of yin deficiency type, 8 cases of qi and yin deficiency type, 5 cases , Damp-heat type in 2 cases, 10 cases. Syndrome Differentiation and Pathological Types: Qi is Mesangial proliferative glomerulonephritis (MsPGN) and MsPGN + focal segmental glomerulosclerosis (FSGS), Yang is sclerosing nephritis (SGN), FSGS, MsPGN + FSGS and MsPGN, Yin is MsPGN, Qi and Yin are MsPGN, MsPGN + FSGS and Capillary proliferative glomerulonephritis (EPGN), hot and humid are focal nephritis (FGN), EPGN and MsPGN. Nephrotic pathological examination can provide objective indicators for syndrome differentiation, and can guide the clinical syndrome differentiation.