本文对４１４例肾移植供、受者ＨＬＡ－ＤＲ血清学分型，共检出ＤＲＩ至ＤＲ１０位点６７１个。供者以ＤＲ２、ＤＲ５，ＤＲ４频率最高，受者以ＤＲ５、ＤＲ２、ＤＲ４占多数。６例受者，２例供者血清学分型失败，占２．０％；１１个ＤＲ位点不肯定，占２．７％；超过半数的ＤＲ２、ＤＲ５、ＤＲ６主要亚型不能分辨：ＤＲ空白位点供者５６个，占１６．６％，受者８５个，占１７．９％。结果显示：血请学方法分型结果欠精细并存在一定的误差率。 In this paper, 414 cases of renal transplantation donor and recipient HLA-DR serological typing, a total of DRI to DR10 were detected 671 points. Donors to DR2, DR5, DR4 the highest frequency, recipients to DR5, DR2, DR4 accounted for the majority. 6 patients and 2 donors had serological typing failure, accounting for 2.0%; 11 DR sites were uncertain, accounting for 2.7%; more than half of DR2, DR5 and DR6 major subtypes could not be distinguished: DR blank 56 donors, accounting for 16.6%, 85 recipients, accounting for 17.9%. The results showed that the blood typing methods were less subtle and had a certain error rate.