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目的:探讨腹腔镜Ladd’s手术与传统开腹手术对小儿先天性肠旋转不良的疗效及免疫功能的影响。方法:选取2008年6月~2015年6月期间笔者所在医院收治的先天性肠旋转不良患儿58例,按照抽签法分为观察组(n=29,腹腔镜)和对照组(n=29,传统开腹)。比较两组患儿术前、术后第1天及第5天血清中细胞免疫指标(CD3+、CD4+、CD8+、NK细胞、B细胞)水平。结果:两组术后第1天比较,除NK细胞差异无统计学意义(P>0.05)外,其余指标差异均有统计学意义(P<0.05)。结论:腹腔镜Ladd’s手术相比传统开腹,对患儿免疫功能抑制较小,创伤小术后恢复快。
Objective: To investigate the effects of laparoscopic Ladd’s surgery and traditional laparotomy on the efficacy and immune function of children with congenital intestinal malrotation. Methods: Fifty-eight children with congenital dysplasia of intestine who were admitted to our hospital from June 2008 to June 2015 were randomly divided into observation group (n = 29, laparoscopy) and control group (n = 29) , Traditional laparotomy). The serum levels of cellular immune markers (CD3 +, CD4 +, CD8 +, NK cells and B cells) in the two groups were compared before and after operation. Results: There was no significant difference between the two groups on the first day after operation (P> 0.05) except NK cells (P> 0.05). Conclusion: Laparoscopic laparoscopic surgery compared with the traditional laparotomy, the suppression of immune function in children with small, traumatic surgery faster recovery.