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目的探索同位素示踪早期检测神经再生的可行性，并与神经电图－肌电图检测结果进行比较，为临床应用奠定基础。方法将鼠坐骨神经切断并作神经缝合，术后１、２、３、４周用微量注射器将１２５Ｉ－酪氨酸直接注射入大鼠坐骨神经干内，于注射后８、１２、１６小时取样以γ－计数器检测其放射性。测定再生神经１２５Ｉ－酪氨酸转运规律，并与神经电图－肌电图检测结果、光镜下再生髓鞘形态学变化相比较。结果术后２周轴浆流即可通过缝合口，早于神经电图－肌电图出现时间；与再生髓鞘出现时间相符。结论应用轴浆流同位素示踪法早期检测神经再生，较神经电图－肌电图具有明显的优越性。
Objective To explore the feasibility of isotope tracing for the early detection of nerve regeneration and to compare with the results of electromyogram and electromyogram to provide the basis for clinical application. Methods The rat sciatic nerve was cut off and sutured nerves. The rats were injected with 125I-tyrosine directly into the sciatic nerve trunk of rats at 1, 2, 3 and 4 weeks after operation. Samples were taken at 8, 12 and 16 hours after injection - Counters detect their radioactivity. The 125I-tyrosine transport patterns of regenerative nerve were measured and compared with the results of electromyogram-EMG test and morphological changes of myelin under light microscope. Results The axillary pulp flowed through the suture mouth two weeks after the operation, earlier than the appearance time of electromyogram and EMG. It corresponded to the appearance of regenerative myelin sheath. Conclusion Early detection of nerve regeneration by using axial flow isotope tracer method has obvious advantages over electromyography.