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对16例糖尿病并高血压、6例单纯糖尿病及配对研究的16例单纯高血压病、6例无糖尿病无高血压尸检病例心脏形态学改变进行观察。结果显示糖尿病、高血压病均可致心脏重量、心脏重量/体重比值增加(P<0.01),心肌纤维化加重,尤以二者并存时病变最显著。心肌细胞平均截面积以有糖尿病组增大明显(P<0.05)。左心室壁厚度以有高血压组增加明显(P<0.05)。提示有高血压病将加重糖尿病的心脏病理改变。
16 patients with diabetes mellitus and hypertension, 6 patients with simple diabetes mellitus and matched controls were studied in 16 cases of simple hypertension and 6 cases of non-diabetic non-hypertensive autopsy cases. The results showed that both diabetes and hypertension could cause cardiac weight, cardiac weight / body weight ratio increased (P <0.01), myocardial fibrosis increased, especially when the two co-exist the most significant lesions. The average cross-sectional area of myocardial cells in patients with diabetes increased significantly (P <0.05). Left ventricular wall thickness in patients with hypertension increased significantly (P <0.05). Prompted hypertension will increase the diabetic pathological changes.