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目的:了解分娩方式对健康产妇血清酶GOT、GPT、γ-GT、ALP、LDH、CK、CK-MB、HBDH的影响及其变化。方法:测定194例健康产妇足月分娩后48h内的血清酶,根据分娩方式将产妇分为阴道产组及剖宫产组,剖宫产又分为择期组及急症组;阴道产又分为顺产组及难产组;分别对各组间各种血清酶升高率进行χ2检验。结果:阴道产组心肌酶GOT、CK、CK-MB、HBDH升高率显著高于剖宫产组(P<0.05~P<0.01);阴道顺产组与难产组比较,除难产组CK升高率显著高于顺产组外,其余心肌酶升高率两组间无差异(P>0.05);剖宫产急症组与择期组间血清酶升高率无差异(P>0.05);各组间肝酶GPT、γ-GT、ALP升高率无差异(P>0.05)。结论:阴道分娩者对心肌的影响大于剖宫产者;分娩方式对心肌的影响取决于胎儿经阴道产抑或剖宫产,而与术式、时机无关。分娩方式对肝酶影响不明显。但尚须积累更多的资料方可定论。
Objective: To investigate the effects of delivery mode on the serum levels of GOT, GPT, γ-GT, ALP, LDH, CK, CK-MB and HBDH in healthy maternal and their changes. Methods: The serum enzymes of 194 healthy pregnant women within 48 hours after delivery were divided into vaginal delivery group and cesarean delivery group according to mode of delivery. Cesarean section was divided into elective group and emergency group. Vagina was divided into Cesarean section and dystocia group; χ2 test was carried out on the rate of various enzymes in each group. Results: The increase rate of myocardial enzyme GOT, CK, CK-MB and HBDH in vaginal delivery group was significantly higher than that in cesarean section group (P <0.05 ~ P <0.01) There was no significant difference between the two groups (P> 0.05). There was no difference in the rate of serum enzyme between cesarean section and elective group (P> 0.05). There was no difference in the increase rate of GPT, γ-GT and ALP between the groups (P> 0.05). CONCLUSION: Vaginal delivery has a greater impact on myocardium than cesarean delivery. The effect of delivery mode on myocardium depends on vaginal delivery or cesarean section, but not on the timing and type of operation. Mode of delivery of liver enzymes is not obvious. However, we must accumulate more information before finalization.