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美国得克萨斯大学卫生科学中心研究人员发展了一项简易试验,可检出家族性高胆固醇血症(FH)患者。如果此试验的高度可靠性在研究中证实,可望用饮食和药物疗法预防冠状动脉疾病及其有关的心脏病发作。 Jennifer Cuthbert等医师取15ml血作低密度脂蛋白(LDL)培养需4~6天。所需时间将随同试验的改进而减少。目前检查纤维细胞的试验需时2~3个月。能作此项试验的不过是6个医学中心。大约500名美国人中有1人(即约50万人)有杂合子遗传倾向,出现高胆固醇血。罕见的
Researchers at the University of Texas Health Science Center have developed a simple test to detect familial hypercholesterolemia (FH). If the high reliability of this trial is confirmed in the study, diet and drug therapy are expected to prevent coronary artery disease and its associated heart attacks. Jennifer Cuthbert and other physicians take 15ml of blood for low-density lipoprotein (LDL) culture takes 4 to 6 days. The time required will be reduced as the trial progresses. The current test of fiber cells takes 2 to 3 months. It is only six medical centers that can do this test. One in about 500 Americans (about 500,000 people) has a heterozygous genetic predisposition to hypercholesterolemia. rare