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目的：观察对老年性肺炎患者行左氧氟沙星序贯疗法治疗的安全性。方法：以医院门急诊及内科2010年6月到2012年6月收治的124例老年性肺炎患者为对象，将其分成治疗组和对照组两组。治疗组患者64例，0.4g/d左氧氟沙星注射液每天两次加入5%葡萄糖注射液或250～500mL生理盐水中静脉滴注，3天后改为每天两次口服左氧氟沙星片0.4g/d。对照组患者60例，也采用0.4g/d左氧氟沙星液加入5%葡萄糖注射液或250～500mL生理盐水中静脉滴注，每天两次，连续治疗8天。治疗组与对照组对其他抗生素都不使用。结果：治疗组患者与对照组患者治愈率分别为93.7%，90.0%。结论：对老年性肺炎患者行左氧氟沙星序贯疗法治疗效果好，既安全又经济，值得临床推广。“,”[OBJECTIVE] To observe the senile patients with pneumonia levofloxacin sequential therapy safety. Methods: 124 patients hospital emergency department senile pneumonia and respiratory medicine in June 2010 to June 2012 were treated as objects, wil be divided into treatment group and control group. Treated 64 patients, 0.4g / d twice levofloxacin in 5%dextrose injection or 250 ~ 500mL saline intravenously every day, three days to two oral levofloxacin tablets 0.4g / d per day. 60 patients in the control group, but also the use of 0.4g/ d levofloxacin solution in 5% dextrose injection or 250 ~ 500mL saline intravenously, twice daily for 8 consecutive days. The treatment group and the control group do not use other antibiotics. Results: The cure rate of patients with the control group of patients treated group were 93.7%, 90.0%. Conclusions: Elderly patients with pneumonia line levofloxacin sequential therapy effective, safe and economical, worthy of promotion.