男性,16岁,学生。多饮,多尿发育差8年,恶心、呕吐2个月,1991年4月6日以“肾小管性酸中毒”收入院。8年前开始烦渴多饮,每昼夜饮水10000ml,尿量相应增多,无易饥多食现象,患者体力差,发育缓慢,智力正常。近两日食欲差,恶心呕吐,有时手足搐搦,口渴多饮加重。父母非近亲结婚,家族成员中无类 Male, 16 years old, student. Drink more, polyuria worse than 8 years of development, nausea, vomiting for 2 months, April 6, 1991 to “renal tubular acidosis” income hospital. 8 years ago began to polydipsia, drinking water every day and night 10000ml, a corresponding increase in urine output, no easy to eat more hungry phenomenon, poor physical performance, slow development, mental retardation. Nearly two days poor appetite, nausea and vomiting, and sometimes tetany, thirsty and more drink aggravating. Parents are married to non-relatives and have no class in their family members