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5. Pharmacophore-based structure optimization of angiotensin converting enzyme inhibitory peptide

Pharmacophore-based structure optimization of angiotensin converting enzyme inhibitory peptide

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：aghdks

【摘 要】

：

Chemical feature based pharmacophore models were generated for an angiotensin converting enzyme(ACE) inhibitory peptide using the Discovery Studio 2.0 pharmacop

【作 者】

：

WANG Wei  SHEN ShengRong  FENG 

【机 构】

：

DepartmentofFoodScienceandNutrition

【出 处】

：

中国科学：化学英文版

【发表日期】

：

2008年8期

【关键词】

：

ANGIOTENSIN CONVERTING ENZYME INHIBITORY peptide PHARMACOPHORE model DOCKING ang 

【基金项目】

：

Supported by the Program 111 of Ministry of Education of China and the Program “National Science and Technology Support Plan of Eleventh Five Year Program-ming” of China (Grant No. 2006BAD05A01)

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Chemical feature based pharmacophore models were generated for an angiotensin converting enzyme(ACE) inhibitory peptide using the Discovery Studio 2.0 pharmacophore modeling approach. The pharmacophore hypothesis selected has five features(one negative io

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