论文部分内容阅读
作者指出:在一些国家随着微生物传染病的控制,遗传性和发育性疾病已显得突出。在美国大城市儿科住院病人中遗传病占40%。遗传病有些与皮肤科特别有关系。随着羊膜穿刺术的发展,许多遗传病已能正确作出出生前诊断,随着体细胞遗传学的迅速进展,象粘多糖病这类严重的遗传病不久也可获有效治疗。在体外用含有相应的遗传信息密码噬菌体染色体组“接种”于一例半乳糖血症患者而使其缺酶的纤维母细胞得到改正,这一试验的成功使人们相信基因疗法的实用性将比想象中的可能性来的更快。故在今后二十几年中遗传学必将在各医学领
The authors note that with the control of microbial infections in some countries, genetic and developmental disorders have become prominent. Genetic disease accounts for 40% of pediatric inpatients in the United States. Some genetic diseases and dermatology are particularly relevant. With the development of amniocentesis, many genetic diseases have been correctly diagnosed before birth. With the rapid progress of somatic cytogenetics, serious genetic diseases such as mucopolysaccharidosis can soon be effectively treated. The success of this trial, which resulted in the correction of fibroblasts lacking enzymes in vitro by inoculation with a phage genome containing the corresponding genetic code for cryptococcosis in one patient with galactosemia, convinced one that the utility of the gene therapy would be more potent than imagination The possibilities are faster. Therefore, in the next two decades, genetics is bound to be in all medical departments