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Aim:Intracranial germinoma is a rare malignant tumour in childhood with an excellent prognosis under adequate therapy.Finding the right diagnosis at an early stage is difficult because of the slow-growing tumour and the resulting lack of clinical symptoms.Methods:Our patients with histologically secured germinoma were retrospectively assessed concerning growth retardation,pituitary hormone status,magnetic resonance imaging scan results and clinical symptoms to find out whether there is a leading parameter.Results:In all our patients,the leading symptom was growth retardation of at least 2 y before being diagnosed.Conclusion:Growth retardation seems to be a very early sign of germinoma in the suprasellar region.Therefore,early neuroradiological imaging combined with pituitary hormone status should be considered in every paediatric patient with a history of secondary growth retardation.
Aim: Intracranial germinoma is a rare malignant tumor in childhood with an excellent prognosis under adequate therapy. Finding the right diagnosis at an early stage is difficult because of the slow-growing tumor and the resulting lack of clinical symptoms. Methods: Our patients with histologically secured germinoma were retrospectively involved growth growth, pituitary hormone status, magnetic resonance imaging scan results and clinical symptoms to find out whether there is a leading parameter. Results: In all our patients, the leading symptom was growth retardation of at least 2 y before being diagnosed. Confc: Growth retardation seems to be a very early sign of germinoma in the suprasellar region. Before, early neuroradiological imaging combined with pituitary hormone status should be considered in every paediatric patient with a history of secondary growth retardation.