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通过研究偏头痛患者血清Ig和DNA抗体水平的改变,探索偏头痛与免疫学的关系。对象与方法按1962年国际头痛分类会议所定诊断标准,随机收集偏头痛患者64例(男33例,女31例),年龄16～55岁,平均29.7岁;病程1～20年,平均3.7年。64例中普通型偏头痛42例,典型偏头痛22例。全部患者均除外免疫障碍性疾病,且均无抗癫痫药、甲基多巴、肼苯哒嗪等药物应用史。以50名献血员作为正常对照,取禁食12小时以上静脉血清4℃冰箱保存。血清Ig测定采用单向免疫扩散法,试剂系上海生物所提供的马抗人IgG、IgA、
To investigate the relationship between migraine and immunology by studying the changes of serum Ig and DNA antibody levels in migraineurs. Subjects and methods According to the diagnostic criteria set by International Headache Classification Conference in 1962, 64 migraineurs (33 males and 31 females) were randomly collected, aged from 16 to 55 years, with an average of 29.7 years. The course of disease ranged from 1 to 20 years (mean, 3.7 years . Of the 64 cases, 42 were common type of migraine and 22 were typical migraine. All patients except for immune disorders, and no antiepileptic drugs, methyldopa, hydralazine and other drug application history. 50 blood donors as a normal control, fasted 12 hours or more venous serum 4 ℃ refrigerator preservation. Serum Ig assay using one-way immunodiffusion, Shanghai Institute of Biological reagents provided by the anti-human IgG, IgA,