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在筛选免疫抑制剂的过程中，找到了一株吸水类链霉菌Ｉ２１９０，属于ＦＫ－５０６类化合物的产生菌，从其发酵产物中已分离出Ａ、Ｂ二个组份，基于光谱数据和理化特性的分析，证实１２１９０Ｂ和免疫抑制剂ＦＫ－５２０及ＬＤ－６８３５９０（Ｉｍｍｕｎｏｍｙｃｉｎ）均为同一物质。
In the screening of immunosuppressants, a strain of Streptomyces hygroscopicus I2190, belonging to the FK-506 class of bacteria, was isolated from which A and B components had been separated. Based on spectral data and physicochemical properties Characterization confirmed that 12190B and immunosuppressive agents FK-520 and LD-683590 (Immunomycin) are the same substance.