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季节性花粉症(以下简称花粉症)是属于Ⅰ型变态反应,通过一系列过程释放组胺等多种介质,导致粘膜水肿,血管内液体渗出、分泌物增多、局部刺激和平滑肌收缩等。临床主要表现为鼻痒、喷嚏连续发作、流大量清水样鼻涕、鼻塞等;有的患者还可发生眼痒、流泪、结膜充血、哮喘等。本研究通过我疾病控制中心变态反应科长期探索,对296例花粉症患者进行了快速免疫治疗,于次年花粉症发病季节后复诊,记录其中临床症状的变化情况,并再次进行变应原测定,对治疗效果进行评价。现将有关资料报道如下。
Seasonal hay fever (hereinafter referred to as hay fever) is a type Ⅰ allergy, through a series of processes such as histamine release a variety of media, leading to mucosal edema, intravascular fluid exudation, increased secretions, local irritation and smooth muscle contraction. The main clinical manifestations of nasal itching, sneezing continuous attack, a large number of water samples runny nose, nasal congestion, etc .; some patients may also occur itchy eyes, tears, conjunctival congestion, asthma and so on. In this study, 296 cases of hay fever patients were treated with rapid immunotherapy through the long-term exploration of the Allergy Division of the Centers for Disease Control and Prevention. The patients were referred for treatment after the onset of the second year of hay fever and the changes of clinical symptoms were recorded. , The treatment effect was evaluated. The relevant information is reported below.