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中毒性休克综合征(TSS)是以突然高热、频繁吐泻、皮疹、脱皮、严重休克等多系统损害为主要特征的临床综合征,1927年已有类似病例报告.1978年Todd等报导7例,其中5例于咽、阴道等粘膜部位及局部脓液中培养出金黄色萄葡球菌(金葡菌),噬菌体分型属Ⅰ和Ⅲ组,血培养均阴性,首先命名为TSS.近来发现TSS并不少见.至1982年4月9日,美国亚特兰大的疾病控制中心(CDC)已收到1,660例TSS的病例报告.其中1980年为867例,1981年为492例,死亡率5.6%.
Toxic shock syndrome (TSS) is a clinical syndrome characterized by sudden high fever, frequent vomiting, skin rashes, peeling, severe shock and other multisystemic lesions, with similar cases reported in 1927. Todd et al.7 reported in 1978, Among them, 5 cases of Staphylococcus aureus (Staphylococcus aureus) were cultured in pharynx, vagina and other mucous membranes and local pus. The phage genotypes belong to group Ⅰ and Ⅲ, and their blood cultures were negative, first named as TSS. Not uncommonly, up to April 9, 1982, the Centers for Disease Control (CDC) in Atlanta, USA, has received 1,660 cases of TSS, 867 in 1980, 492 in 1981 and a 5.6% mortality rate.