甲氧萘丙酸钠是一种应用广泛的非甾体类消炎镇痛药.作者报告一例患者应用该药诱发肺嗜酸粒细胞浸润症(PIE).患者男,45岁.因强直性脊柱炎17年,咳嗽,前额痛,全身不适和盗汗2周.在用甲氧萘丙酸钠治疗19天时症状突然出现,在此之前他曾用保泰松15年,其后用炎痛喜康18个月.未用过其他药物,既往无过敏反应史.检查体温,脉搏和血压正常.主动脉区可闻及Ⅰ级舒张期杂音.呼吸系统无异常体征.除轻度强直性脊柱炎特征外,其余检查正常.胸透两肺上野外带浸润性病变.起初,临床曾诊断为胸膜-肺纤维化,强直性脊柱炎和肺结核.入院后进一步检查,WBC6.9× Naproxen sodium is a widely used non-steroidal antiinflammatory and analgesic.The authors report a case of patients using the drug induced pulmonary eosinophilic infiltration (PIE) .Patients male, 45 years old due to ankylosing spine 17 years of inflammation, cough, forehead pain, general malaise and night sweats 2 weeks in the treatment with sodium naproxen 19 days when symptoms suddenly appear, before he had used phenylbutazone 15 years, followed by inflammatory pain Xikang 18 months. No other drugs used, no previous history of allergic reactions. Check the body temperature, pulse and blood pressure. Aortic area can be heard and Ⅰ grade diastolic murmur. No abnormal respiratory system. In addition to mild ankylosing spondylitis characteristics , The rest of the examination was normal .Both chest through the upper lung with invasive lesions .First, the clinical diagnosis of pleural - pulmonary fibrosis, ankylosing spondylitis and pulmonary tuberculosis.Further check after admission, WBC6.9 ×