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目的比较急性胃炎患者应用阿托品联合奥美拉唑与山莨菪碱联合奥美拉唑治疗的临床疗效。方法将2013年1月~2014年8月我院收治的90例急性胃炎患者为研究对象,随机平均分成两组,观察组与对照组,每组各45例。对照组患者给予山莨菪碱联合奥美拉唑治疗,观察组患者给予阿托品联合奥美拉唑,比较两组患者的临床疗效及不良反应发生情况。结果观察组患者显效32例(71.1%),有效11例(24.4%),总有效率为95.6%,明显高于对照组总有效率75.6%;观察组患者不良反应的发生率仅为6.7%,远低于对照组28.9%,两组比较差异有统计学意义(P<0.05)。结论急性胃炎患者应用阿托品联合奥美拉唑能够迅速缓解疼痛、反酸等临床症状,疗效确切且不良反应小,较应用山莨菪碱联合奥美拉唑治疗安全性和有效性更为明显,值得在临床推广。
Objective To compare the clinical efficacy of atropine and omeprazole combined with anisodamine and omeprazole in patients with acute gastritis. Methods Ninety patients with acute gastritis treated in our hospital from January 2013 to August 2014 were randomly divided into two groups, observation group and control group, with 45 cases in each group. Patients in the control group were treated with anisodamine combined with omeprazole. Patients in the observation group were given atropine combined with omeprazole. The clinical efficacy and adverse reactions of the two groups were compared. Results The observation group was significantly improved in 32 cases (71.1%), effective in 11 cases (24.4%), the total effective rate was 95.6%, significantly higher than the control group, the total effective rate was 75.6%; the incidence of adverse reactions in the observation group was only 6.7% , Much lower than that of the control group (28.9%). There was significant difference between the two groups (P <0.05). Conclusion Atropine combined with omeprazole in patients with acute gastritis can quickly relieve pain, acid reflux and other clinical symptoms, the curative effect is clear and the adverse reaction is small, the application of anisodamine and omeprazole in the treatment of safety and effectiveness is more obvious, it is worth In clinical promotion.