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目的:观察多磺酸黏多糖乳膏联合磺胺嘧啶银霜剂对深度烧伤的临床疗效。方法:深Ⅱ度烧伤患者128例随机分为对照组和观察组。对照组患者接受磺胺嘧啶银霜进行治疗,观察组患者接受多磺酸黏多糖乳膏联合磺胺嘧啶银霜剂进行治疗。比较两组患者治疗7d和14d的疼痛评分、创面细菌培养情况及创面完全愈合率,以及两组创面完全愈合时间。结果:治疗7d和14d时两组患者的疼痛评分差异有统计学意义(P<0.01),治疗14d和28d时两组患者的创面完全愈合率以及创面完全愈合时间差异具有统计学意义(P<0.01),而两组治疗7d和14d时创面细菌培养情况差异无统计学意义(P>0.05)。结论:多磺酸黏多糖乳膏联合磺胺嘧啶银霜剂可减轻深Ⅱ度烧伤疼痛,并促进创面愈合,值得临床推广。
Objective: To observe the clinical effect of mucopolysaccharide polysulfate cream combined with sulfadiazine silver cream on deep burn. Methods: 128 cases of deep second degree burn were randomly divided into control group and observation group. Patients in the control group were treated with silver sulfadiazine cream. Patients in the observation group were treated with mucopolysaccharide polysulfate cream and silver sulfadiazine cream. The pain score, wound bacterial culture and wound healing rate were compared between the two groups on the 7th day and the 14th day after treatment, and the complete wound healing time was compared between the two groups. Results: There was significant difference in pain score between the two groups on the 7th day and the 14th day after treatment (P <0.01). The complete wound healing rate and complete healing time of the two groups were statistically significant at the 14th day and the 28th day (P < 0.01). However, there was no significant difference in wound bacterial culture between the two groups on the 7th day and the 14th day (P> 0.05). CONCLUSION: Sulfasalazine cream combined with mucopolysaccharide polysaccharide cream can relieve the pain of deep second-degree burns and promote wound healing, which is worthy of clinical promotion.