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(一) 近几年来,对急性肾功能衰竭(ARF)的研究有很大进展。虽然目前对究竟是否存在多尿型ARF尚有争论。1979年Smolens等倾向于把血肌酐在短期内大于2 mg%,不管病人的尿量如何认为是ARF。(二) 在发病原因方面,各种原因休克引起的肾缺血,早就认为是ARF的主要原因,此外发现体液丢失至第三间隙,不适当的使用血管扩张剂,充血性心力衰竭、肾病综合征及肝硬化腹水,都使肾血液灌注减少。肾毒物质及革兰氏阴性菌败血症产生ARF的
(A) In recent years, research on acute renal failure (ARF) has made great progress. Although there is still controversy over whether or not there is polyuria ARF. In 1979, Smolens et al. Tended to have serum creatinine greater than 2 mg% in the short term irrespective of patient’s urine output as ARF. (B) in the pathogenesis, various causes of shock caused by renal ischemia, ARF has long been considered the main reason, in addition to fluid loss found to the third gap, improper use of vasodilators, congestive heart failure, kidney disease Syndromes and cirrhosis ascites, renal blood perfusion are reduced. Nephrotoxic agents and Gram-negative sepsis produce ARF