血吸虫病是一种危害十分巨大的人畜共患寄生虫病,目前主要应用吡喹酮等少数几种化学药物对其进行治疗。在寻找新的抗血吸虫药物研究中,发现一些来源于植物中的天然产物有抗血吸虫活性,同时部分化合物还拥有化学合成抗血吸虫药物所不具有的预防血吸虫病等作用。本文对具有抗血吸虫活性的天然产物进行综述,为抗血吸虫药物研发提供参考。 Schistosomiasis is a very harmful zoonotic parasitic disease, the main application of praziquantel and a few other chemicals for its treatment. In the search for new anti-schistosome drug research, some natural products derived from plants were found to have anti-schistosome activity, and some of the compounds also have the effect of preventing schistosomiasis, which is not found in chemically synthesized anti-schistosome drugs. In this paper, the natural products with anti-schistosome activity were reviewed to provide reference for the development of anti-schistosome drugs.