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日本Nomura等报告,肝细胞癌(HCC)组织中多聚二磷酸腺苷中国肿瘤2000年第9卷第8期(ADP)核糖基化和多聚(ADP核糖)聚合酶(PARP)表达增加。5例HCC患者在手术切除时取肿瘤组织和邻近非肿瘤组织,用32P标记的辅酶Ⅰ使组织匀浆发生ADP核
Japan Nomura et al. Reported that the expression of ribosylated and poly (ADP ribose) polymerase (PARP) increased in hepatocellular carcinoma (HCC) tissues. In 5 cases of HCC patients, the tumor tissues and adjacent non-tumor tissues were removed at the time of resection. The ADP nucleus was homogenized with 32P-labeled coenzyme I