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速尿为强效利尿药,但应用不当,亦可引起内分泌异常、浮肿或浮肿加重。本文报告1例,均为女性,年龄23～28岁。3例为特发性浮肿,1例原因不明性肾脏病。速尿用量40～600mg/d。以下仅介绍其中1例。患者女性,28岁,护士。1975年因患特发性浮肿,口服速尿40mg/d,浮肿消退。1977年因再度出现浮肿,口服速尿40mg/d,后浮肿加重而入院。体查除双下肢轻度浮肿外,余无明显异常发现,心、肝、肾、甲状腺功能正常。水排泄试验符合特发性浮肿,速尿立位负荷试验:试验前血浆肾素活性(PRA)2.20、
Furosemide is a potent diuretic, but improper application can also cause endocrine abnormalities, edema or edema aggravated. This article reports 1 case, all female, aged 23 to 28 years old. 3 cases of idiopathic edema, 1 case of unknown kidney disease. Furosemide dosage 40 ~ 600mg / d. The following describes only one of them. Patient female, 28 years old, nurse. 1975 due to idiopathic edema, oral furosemide 40mg / d, edema subsided. 1977 due to re-emergence of edema, oral furosemide 40mg / d, increased edema and admission. Physical examination except for mild lower extremity edema, I found no significant abnormalities, heart, liver, kidney, thyroid function is normal. Water excretion test in line with idiopathic edema, furosemide vertical position load test: pre-test plasma renin activity (PRA) 2.20,