患者女性,42岁,因关节变形、活动障碍2年于1990年6月4日入院.自1980年始患者左肘、双踝关节肿痛并渐累及双手、腕、肘关节,有晨僵,曾在外院抗风湿治疗仍迁延不愈,于劳累后出现心悸气急,休息后可缓解,无发热、咳嗽、咯血及夜间阵发性呼吸困难.体检:神清,二尖瓣区触及舒张期震颤,两肺听诊正常.心率76次/分,律齐,二尖瓣区闻隆隆样舒张期杂音,并有Ⅲ～Ⅵ级收缩 Female patient, age 42, due to joint deformity, mobility disorder 2 years admitted to hospital on June 4, 1990. Since 1980, patients with left ankle had bilateral ankle joint swelling and pain and became involved with both hands, wrists and elbows with morning stiffness Anti-rheumatic treatment in the outer hospital is still delayed healing, after exertion palpitations, anxiety, rest can ease, no fever, cough, hemoptysis and nocturnal paroxysmal dyspnea.Medical examination: Shen Qing, mitral valve area and diastolic tremor, Both lung auscultation normal heart rate 76 beats / min, law Qi, mitral valve area rumbled diastolic murmur, and Ⅲ ~ Ⅵ contraction