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目的:评价头孢地尼颗粒剂治疗儿童急性化脓性中耳炎的疗效及安全性。方法:将门诊急性化脓性中耳炎患儿分为治疗组和对照组,每次分别口服头孢地尼颗粒剂5mg·kg-1,tid,头孢呋辛酯片15mg·kg-1,bid,疗程10d。结果:治疗组有效率94.6%;对照组有效率82.0%,2组有效率比较差异具有显著性(P<0.05),治疗组细菌清除率94.4%,对照组细菌清除率73.3%,2组细菌清除率比较差异具有显著性(P<0.05)。结论:头孢地尼颗粒剂治疗儿童急性化脓性中耳炎安全有效。
Objective: To evaluate the efficacy and safety of cefdinir granules in the treatment of acute suppurative otitis media in children. Methods: The children with acute suppurative otitis media were divided into treatment group and control group, each time taking cefdinir granules 5mg · kg-1, tid, cefuroxime axetil tablets 15mg · kg-1, bid for 10 days . Results: The effective rate of the treatment group was 94.6%; the effective rate of the control group was 82.0%; the effective rate of the two groups was significant (P <0.05); the bacterial clearance rate was 94.4% in the treatment group and 73.3% in the control group; Clearance rate was significantly different (P <0.05). Conclusion: Cefdinir Granule is safe and effective for children with acute suppurative otitis media.