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新生儿狼疮综合征(NLS)是以皮肤狼疮或先天性心脏传导阻滞(CHB),或两者兼有为特征的疾病。本病罕见,最近才有其临床特征和发病机理的描述。作者研究了14例患儿(超过已报告过病例的15%)。本文目的是总结新生儿狼疮(NL)的临床特征,不断改进观察,增加对新生儿NLS的理解。患婴的临床和实验室所见皮肤是NLS首先报告受累的器官,病变较常见于女婴。41例有皮肤病变的NLS中仅7例为男性。作者报告的14例中,有皮肤
Neonatal lupus syndrome (NLS) is a disease characterized by cutaneous lupus or congenital heart block (CHB), or both. The disease is uncommon and has only recently described its clinical features and pathogenesis. The authors studied 14 patients (over 15% of reported cases). The purpose of this article is to summarize the clinical features of neonatal lupus (NL), to improve observation and to improve understanding of neonatal NLS. The clinical and laboratory findings of infants with the skin are the first reported organs in NLS and the lesions are more common in girls. Only 41 of the 41 NLS patients with skin lesions were men. Of the 14 cases reported by the authors, there was skin