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作者报告一例出生时即诊断为严重Ⅸ因子缺乏患儿，在出生１０个月起接受单核隆Ⅸ因子（Ｍｏｎｏｎｉｎｅ）治疗，剂量为１００ｕ／ｋｇ隔日注射，１岁时出现血清中抗Ⅸ因子抗体，１４个月时接受免疫耐受及抗原脱敏疗法，并增加Ｍｏｎｏｎｉｎｅ量至１００ｕ／ｋｇ／天。２３个
The authors report that one child diagnosed with severe factor IX deficiency at birth was treated with Mononine at 10 months after birth at a dose of 100 u / kg every other day. Serum anti-factor IX antibodies were present at age 1 , Immunosuppression and antigen desensitization therapy at 14 months, and an increase in Mononine to 100 u / kg / day. 23