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血钙>15mg/dl为严重高钙血症,系内科急症,需立即治疗.基本措施是补充生理盐水和速尿等利尿剂,因机体排钠和排钙为同一途径,随着尿钠排出增加,尿钙的清除也增多.但顽固性高钙血症,则需另外增加药物治疗.关于磷酸盐的应用问题,早在1932年Fuller Abright就认识到应用此药可以降低血钙,但他告诫说:此药可致血管内磷酸钙沉淀,不能常规应用.1966年Goldsmith等总结了15例恶性疾病和4例甲旁亢引起的高钙血症,应用磷酸盐者10例死亡,其中7例作了尸检,5例发现有迁移性骨外钙化,作者认为这与磷酸盐的应用无关.此后,本药治疗高
Serum calcium> 15mg / dl for severe hypercalcemia, Department of Medical Emergency, need immediate treatment.The basic measure is to add saline and furosemide and other diuretics, because the body of sodium and calcium discharge for the same route, with the urinary sodium excretion Increase, urinary calcium clearance also increased.However, intractable hypercalcaemia, the need for additional drug therapy.Phosphate application, as early as 1932, Fuller Abright realized that the application of this medicine can reduce blood calcium, but he Caution: This medicine can cause intravascular calcium phosphate precipitation, can not be routinely applied .1966 Goldsmith et al summarized 15 cases of malignant disease and 4 cases of hyperparathyroidism caused by hypercalcemia, 10 cases of phosphate death, of which 7 Case of autopsy, 5 cases of migratory extracranial calcification, the authors believe that this has nothing to do with the application of phosphate. Since then, the drug treatment of high