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作者以前曾报道在临床上发现过血吸虫性肾病,且可发展成终末肾衰。对其治疗仍然很陌生。为了寻求血吸虫性肾病的治疗,本研究进行了三种治疗试验。对象和方法:将26名活动性血吸虫感染有肾脏受累的病人,随机分成三组。分别测定24小时尿蛋白,SCr、Ccr、SPA/G、血胆固醇、C_3、C_4、L、E细胞、抗-DNA、C-反应蛋白、ASO、空腹和餐后血糖。肾活检标本分成二块:一块用作免疫荧光(IF)检查,包括直接IF法:肾组织切片用萤光标记的抗人IgG、IgM、IgA、C_3、C_4、_1q和FRA染色;间接IF法:冰冻切片用单克隆抗血吸虫性
The authors have previously reported clinically found schistosomiasis nephropathy and can develop into terminal renal failure. Its treatment is still unfamiliar. In order to seek the treatment of schistosomiasis nephropathy, the study conducted three treatment trials. Objects and Methods: Twenty-six active schistosomiasis patients with kidney involvement were randomly assigned to three groups. 24 hours urine protein, SCr, Ccr, SPA / G, blood cholesterol, C_3, C_4, L, E cells, anti-DNA, C-reactive protein, ASO, fasting and postprandial blood glucose were measured. Kidney biopsy specimens were divided into two sections: one for immunofluorescence (IF) examination including direct IF method: kidney sections were stained with fluorescently labeled anti-human IgG, IgM, IgA, C_3, C_4, _1q and FRA; : Monoclonal anti-schistosomes for frozen sections