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近年来由于生态学特别是微生态学的飞速发展使我们对很多疾病的发生发展有了新认识。关于急慢性肝病过程中可引起肾脏损害,早被人们所认识,但从微生态学观点讨论这一问题尚不多见,笔者认为有必要根据微生态学理论对这一问题重新认识。既往的观点认为肝病引起肾损害的机制有如下几点。①HBsAg引起的免疫复合物肾炎。②与内毒素血症有关。肝硬化由于网状内皮系统机能受损以及侧支循环形成,肠道细菌毒素进入体循环,内毒素能使肾血管强烈收缩,影响肾血流动力学。内毒素能使尿
In recent years, due to the rapid development of ecology, especially micro-ecology, we have gained a new understanding of the occurrence and development of many diseases. About acute and chronic liver disease can cause kidney damage, people have long been recognized, but from the micro-ecological point of view to discuss this issue is rare, I think it is necessary to re-understand this issue based on micro-ecological theory. The past point of view that the mechanism of liver damage caused by kidney damage are the following points. ① HBsAg-induced immune complex nephritis. ② and endotoxemia related. Liver cirrhosis due to reticuloendothelial dysfunction and collateral circulation formation, intestinal bacterial toxins into the systemic circulation, endotoxin can make a strong contraction of renal vessels, affecting renal hemodynamics. Endotoxin can make urine