论文部分内容阅读
目的:探讨胎儿外监护仪在产力监测中的价值以及胎盘后血中肾上腺髓质素(ADM)的浓度与子宫收缩强度之间的关系。方法:78例产妇根据分娩方式分为3组:阴道自然分娩组,阴道分娩但使用缩宫素组,阴道助产与剖宫产组。应用胎儿外监护仪并根据MU计算3组子宫收缩强度,用放射免疫的方法测定胎盘后血中的ADM的浓度。结果:3组潜伏期sMU值比较无差异,阴道助产与剖宫产组活跃期sMU值明显低于经阴道自然分娩组,且胎盘后血中ADM浓度明显高于经阴道自然分娩组。结论:胎儿外监护仪虽然可以评估产力的变化,但是子宫收缩强度个体间差异较大,因此监测每个产妇产程过程中产力的动态变化更有助于及时发现异常情况;ADM可能抑制子宫平滑肌的收缩,其机理尚需进一步探讨。
OBJECTIVE: To investigate the value of fetal monitoring in the monitoring of labor force output and the relationship between adrenomedullin (ADM) concentration in placental blood and uterine contractility. Methods: According to mode of delivery, 78 maternal women were divided into 3 groups: spontaneous vaginal delivery group, vaginal delivery but oxytocin group, vaginal delivery and cesarean section group. Applying an extra-fetal monitor and calculating the contractile strength of the uterus in three groups according to the MU, the concentration of ADM in the placental blood is determined by radioimmunoassay. Results: There was no difference in sMU between three groups. The sMU value of vaginal delivery and cesarean section was significantly lower than that of vaginal delivery group. The concentration of ADM in placenta was significantly higher than that of transvaginal spontaneous delivery group. CONCLUSION: Although the fetal monitor can assess the change of the output, the uterine contractile strength varies a lot among the individuals. Therefore, monitoring the dynamic changes of the labor force in every parturient is more helpful to discover the abnormal situation in a timely manner. ADM may inhibit the uterine smooth muscle Contraction, the mechanism still needs to be further explored.