Objective The purpose of this study was to identify the feature genes which are related to Hereditary Hemochromatosis (iron overload) in the cardiac and skeletal muscle of mice.Methods We downloaded t
Objective To observe the effect of radiation on clinical symptoms,immunologic function,chromosome aberration and telomerase activity of bone marrow mononuclear cells(BMNC) in humans exposed to 192Ir p
Objective To clone the variable region genes of human anti-IL1RAP(IL-1 receptor accessory protein) monoclonal antibody(McAb) and construct IL1RAP chimeric antigen receptors(CARs).Methods The VH and VL
Aim Immune suppressor cells play an important role in impaired immune system.Myeloid-derived suppressor cells (MDSCs) are heterogeneous,immature,myeloid progenitor cells,which can suppress immune func
Objective As a newly discovered tumor associated antigen,epidermal growth factor receptor pathway substrate 8 (Eps8) has been found over expressed not only in leukemia blast cells of patients with acu
Chromosomal ends are protected from degradation and DNA repair activities by telomeres.Telomere maintenance depends on precise associations between telomeric DNA and its associated proteins.Telomeric
Thymus provides the basic architecture for development of thymocytes.Although being sensitive to invasion,the thymus in adolescent is resilient after impairment.Intrathymic IL-22 has been proved to be
Objective Efficiency of intravascular delivery of mesenchymal stem cells has been limited as most mesenchymal stem cells given by this route are trapped in the lung.This study aimed to evaluate the ho