2. 您的位置
3. 首页
4. 会议论文
5. Arginine analogue-modified PAMAM leads to enhanced gene transfection efficiency

Arginine analogue-modified PAMAM leads to enhanced gene transfection efficiency

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：zhang504752895

【摘 要】

：

Dendrimers have been extensively explored as non-viral vectors due to their inherent advantages including well-defined monodisperse structure,ample surface groups for functionalization and low intrins

【作 者】

：

Jiajia Xiang Quan Zhou Xin Liu Xiangrui Liu Jianbin Tang Zhuxian Zhou Youqing Shen 

【机 构】

：

Center for Bionanoengineering and Key Laboratory of Biomass Chemical Engineering,Ministry of Educati

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

gene delivery transfection PAMAM arginine analogue 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Dendrimers have been extensively explored as non-viral vectors due to their inherent advantages including well-defined monodisperse structure,ample surface groups for functionalization and low intrinsic viscosity in solution[1].

其他文献

Bio-inspired polydopamine coated PLGA nanoparticles for light induced cancer thermos chemotherapy

Most photothermal converting systems are not biodegradable,which can bring the uneasiness when they are administrated into human body due to the uncertainty of their fate[1,2].Hereby,we developed a mu

会议

polydopaminetargetingdrug deliverychemotherapythermotherapy

A pH-sensitive cationic micelle for siRNA delivery

With the discovery of RNA interference technology,small interference RNA (siRNA) has become a very important tool for cancer therapy[1].However,carriers are needed for transporting siRNA to tumor tiss

会议

cationic micellestimuli-responsivesiRNA deliveryschiff base bond

Reduction-sensitive functional mesoporous silica nanoparticles for dual-drug-delivery

Mesoporous silica nanoparticles (MSNs) have evidenced to be an effective drug delivery system[1].It is well documented that the gatekeeper of the drug carriers has serious impact on the controlled dru

会议

reduction-sensitivedual-drug-deliverymesoporous silica nanoparticlecancer the

Introduction of an AIE fluorophore into cationic gene delivery vehicles verified the nuclear translo

Gene therapeutic approach rooted in the concept of engineering nanoparticulates as gene delivery vehicles to accommodate therapeutic DNA sequences and deliver them into the nucleus of the targeted dis

会议

gene deliveryaggregation-induced-emissiontetraphenylethenepolyethylenimineca

Multifunctional nanotherapeutics for tumor-targeted drug/gene co-delivery

Synergistic therapeutics have been demonstrated as means for effective tumor therapy,while the co-loading of cargoes with different mechanism all-in-one is always a challenge[1].Polyethyleneimine (PEI

会议

pH-sensitivehydrazone bondcytotoxicitytransfection efficiencyco-delivery

An improved pH-responsive carrier based on EDTA-Ca-Alginate for oral delivery of Lactobacillus rhamn

A pH-responsive carrier based on an ethylenediaminetetraacetic-calcium-alginate (EDTA-Ca-Alg)system was developed by controlling the release of Ca2+.The system remained in the solution state at neutra

会议

hydrogelEDTA-Ca-AlgpH-responsive carrierLactobacillus rhamnosuscontrolled re

Synthesis of hyperbranched polyglycidol-block-poly(L-lactide) for pH-sensitive controlled drug deliv

A series of novel and biocompatible hyperbranched polyglycidol-b-poly(L-lactide) (HBP-b-p(L-lactide)n) (n =10,20,30 and 40) copolymers have been successfully synthesized by anionic ring-opening multi-

会议

block copolymerdrug deliveryhyperbranched polymermicellespoly(L-lactide)pH-

Functionalizing polyplex surface through self-assembly of a rationally designed tri-block copolymer

While rationally designed cationic polymers or cationic lipids may easily condense anionic nucleic acids into nano-particles of desired sizes and escape to cytoplasm after endocytosis,reaching the tar

会议

polywraplexself-assemblyblock-copolymer membranecell-targeting

Screening of efficient carriers for intracellular protein delivery in library of fluorinated dendrim

Protein therapy has been considered as one of the most promising and safest approaches in the treatment of many diseases during the past two decades.Protein therapeutics such as growth factors,cytokin

会议

protein deliverydendrimerfluorinated polymerlibraryself-assembly

The drug delivery system based on porous carbon nanofibers

Porous carbon nanofiber (PCNF) has received rising attention as carrier for catalyst recently[1],because of its strong adsorption ability,high specific surface area and numerous of pores on the nanofi

会议

electrospinningporous carbon nanofiberdrug deliverydrug carrier