Modified nucleotides,especially those related to epigenetic or epitranscriptomicfunctions,provide critical regulatory information beyond their sequence and alsodefine cell status in higher organisms.
Protein folding occurs as a set of transitions between structural states within an energy landscape.An oversimplified view of the folding process emerges when transiently populated states are undetect
Many nanomaterials can be used as sensors or transducers in biomedical research and they form the essential components of transformative novel biotechnologies.In this study,we present an all-optical m
The intracellular microenvironment including polarity and pH is the feedback of a series of complex mechanisms that establish and maintain functionally of particular domains.
ESIPT(excited-state intramolecular proton transfer)is emerging as a new design principle for fluorescence probes and attracts extensive attention in many fields of chemical and biological sciences for